Vibrio cholerae bacteria. On November 2014, some members of the CSQUID team published a study on cholera transmission in Bangladesh in the PLoS Neglected Tropical Diseases journal. Participating researchers included Jonathan Sugimoto, Eben Kenah, Elizabeth Halloran, Yang Yang, and Ira Longini. The study quantified…
The waning number of Ebola cases is good news for West Africa, but for those developing a vaccine for the disease, it means time is running short. As the current outbreak wanes, scientists have to make the most of every opportunity to determine if an Ebola vaccine…
CSQUID has conducted research on the Ebola virus and projection models. For questions about our Ebola research please visit http://www.mobs-lab.org/ebola.html. …
We use mathematical and computer models of infectious disease transmission to simulate the course of epidemics and evaluate the efficacy of mitigation strategies. Recent projects include modeling pandemic H1N1 in the US, cholera in Haiti, and dengue in Thailand. Chao DL, Halloran ME,…
We use causal inference to evaluate the indirect, total and overall effects of vaccination. We are currently involved in designing or analyzing data from field trials of influenza vaccination in Senegal and dengue vaccination. The effects of vaccination vary at the individual and at the population level. Even unvaccinated individuals…
We develop methods to estimate transmission parameters from studying outbreaks in close contact groups. Yang Y, Halloran ME, Daniels MJ, Longini IM Jr. Modeling competing infectious pathogens from a Bayesian perspective: Application to influenza studies with incomplete laboratory results.
We are using epidemic percolation networks and survival analysis to estimate transmissibility of infectious disease. We argue that the time from the onset of infectiousness to infectious contact, which we call the “contact interval,” is a better basis for inference in epidemic data than the generation or serial interval. Since…
We study both the ecological determinants that drive cholera transmission seasonality and the potential use of vaccines to mitigate or prevent outbreaks. We are measuring ecological determinants of cholera transmission in Bangladesh. See our publication “Epidemic and endemic cholera trends over a 33-year period in Bangladesh”…
Our emphasis is on the use of coming dengue vaccines for the control and elimination of dengue in targeted geographic area. This work involves the analysis of dengue data from selected field sites in Thailand, Colombia and Nicaragua. In addition, we have developed an agent-based model of dengue transmission to…
