Our emphasis is on the use of coming dengue vaccines for the control and elimination of dengue in targeted geographic area. This work involves the analysis of dengue data from selected field sites in Thailand, Colombia and Nicaragua. In addition, we have developed an agent-based model of dengue transmission to estimate the effectiveness of mass vaccination. The model is closely based on the demography of the Bang Phae district in Ratchaburi, Thailand. We plan to expand the model to include other populations that will be using dengue vaccines. This work is joint with the Dengue Vaccine Initiative http://www.denguevaccines.org/ .
Funding provided by
The Bill and Melinda Gates Foundation, Dengue Vaccine Initiative http://www.denguevaccines.org/ and Models of Infectious Disease Agent Study (MIDAS) sponsored by the National Institute of General Medical Sciences (NIGMS).